ghrelin

The research is pretty clear this is from ghrelin stimulating appetite and at the same time altering levels of leptin so a person feels less full.

His body is demanding increased caloric intake (via insulin, leptin, and ghrelin) to maintain fat stores.

This article about ghrelin is yet another piece of the puzzle of why IF works so well for some people.

But there are other hormones that can impact weight as well, such as cortisol (stress hormone), ghrelin (hunger response hormone) etc.

It wouldn't be shocking that at extreme use ghrelin stops acting without stimulation from cannabis.

When I actually break my fast I can feel the changes in the gut, mood, Ghrelin production, etc...

He’s probably thinking of ghrelin (or NPY), but leptin and insulin both act as satiety signals too, although weaker than the hunger signal.

Leptin controls satiety, whilst the release of ghrelin induces the feeling of hunger.

Also involved: leptin, ghrelin, glucagon, cortisol and probably dozens of others neither of us will hear of in our entire lifetimes.

Ghrelin and dopamine are strongly linked, and dopamine is our central reward-seeking driver; GLP-1s generally reduce ghrelin production, which I suspect helps remove you from a state of being constantly primed for reward-seeking.

I have never heard of this but cannabis has a powerful effect on ghrelin.

Did you know that ghrelin was only discovered in 1999?

Again my friend read carefully: we both totally agree in “ghrelin levels determine hunger”.

Then when overeating destroyed your hormonal balance (insulin, ghrelin are appetite regulating hormones that which imbalance can make a tiny bit of hunger massive and painfull), it's extremely hard to adopt "normal" eating habits without a lot of stability in your life.

"The rise in ghrelin is independent of meal timing as demonstrated by similar peaks before an anticipated meal in various meal frequencies, thus suggesting that subjective feelings of hunger and energy intake is highly dependent on the individual’s preferred meal pattern (76)."