vasodilation

Magnesium plays a part on vasodilation regulation as well, and many people are silently deficient on it.

Caffeine --> Adenosine anatagonist (nonselective A1, A2A, A2B) --> Inhibition of vasodilation --> Cerebral vasoconstriction 6.

Direct effects on brain physiology: When CO2 levels rise in the blood (hypercapnia), it causes vasodilation of cerebral blood vessels.

The release of NO into the bloodstream can secondarily trigger other chemical pathways involved in vasodilation and reactive oxygen species management.

Presumably to boost oxygen to the brain you'd need to increase blood flow (vasodilation or heart-rate) or increase oxygenation of the blood.

One last thing worth looking into is the link between vasodilation and cluster headaches.

Yeah, caffeine is not the cause per se - the thing is it has both vasoconstriction and vasodilation effects at different times, so it can mess with blood vessels in the inner ear.

Because it has other side effects, ones it was initially designed for: vasodilation.

Stress affects the sympathetic neural system, limiting vasodilation in the gut, reducing the immune system’s cell access to the gut, and so on.

Amlodipine is a calcium-channel blocker which lowers blood pressure by promoting systemic vasodilation.

One supposition can be made: light has been shown to generate NO in the endothelium, which through a cascade of events leads to vasodilation.

Caffeine is likely needed for -adenosine, vasculature effect implicating cerebral vasodilation 6.

Vasodilation is also the result of exercise, one of the few non-drug related treatment options that decreases RLS symptoms." The above is the basis of my research.

"When you abruptly stop the consumption of caffeine in a habitual consumer, there is a greater number of available adenosine receptors, which potentiates the vasodilation produced by adenosine, causing the symptoms"

Vasodilation and vasoconstriction of blood vessels have a direct impact.