(biochemistry) Any of various enzymes that catalyze the formation of polymers of DNA or RNA using an existing strand of RNA or DNA respectively as a template.
Used in a Sentence
polymerase
Definition, parts of speech, synonyms, and sentence examples for polymerase.
Editorial note
Indeed, 1975 means I would be the first person to think of the idea of Polymerase Chain Reaction!
Examples17
Definitions1
Parts of speech1
Quick take
(biochemistry) Any of various enzymes that catalyze the formation of polymers of DNA or RNA using an existing strand of RNA or DNA respectively as a template.
Meaning at a glance
The clearest senses and uses of polymerase gathered in one view.
Definitions
Core meanings and parts of speech for polymerase.
noun
(biochemistry) Any of various enzymes that catalyze the formation of polymers of DNA or RNA using an existing strand of RNA or DNA respectively as a template.
Example sentences
Indeed, 1975 means I would be the first person to think of the idea of Polymerase Chain Reaction!
A protein complex forms there and polymerase runs down sequentially from nucleotide to the next physically closest nucleotide.
The improvements made by Mullis allowed polymerase chain reaction (PCR) to become a central technique in biochemistry and molecular biology...
DNA is cheap and stable, but the enzymes (reverse transcriptase, dna polymerase) are expensive and unstable.
When something like RNA polymerase goes through DNA, it always goes to the physically closest nucleotide.
No nucleotide can bond to a nucleotide farther away, and have a polymerase follow that bond.
My favorite is the discovery taq polymerase from thermophile bacteria that lives on thermal vents at the bottom of the ocean.
It plays its a normal role as a polymerase catalyzing the elongation of a new DNA molecule by adding a monomer.
Don't forget about DNA and RNA polymerase, which are both very interesting as well.
Even then, physics limits you to something like 1000 read/writes per sec per pore/polymerase.
Look at the polymerase chain reaction, thought up during a late-night drive by a graduate student and now ubiquitous in biology and medicine.
Kary Mullis, the inventor of polymerase chain reaction, is an HIV denialist.
Quote examples
The "nano machine" is a natural or modified polymerase.
Their replication mechanism uses RNA polymerase II, a host cell enzyme normally associated with synthesis of messenger RNA from DNA, which instead catalyzes "rolling circle" synthesis of new RNA using the viroid's RNA as template.
My favorite example is Arthur Kornbergs JBC papers on polymerase in 1957 [1] where the reviewers recommended rejection with amongst others the comment “It is very doubtful that the authors are entitled to speak of the enzymatic synthesis of DNA”.
I thought that "discovered" was very ambiguous (was it intentional?) I wanted to write something offbeat, like, "The Dawson City mayor stole cable TV for all its citizens in 1996" or "DNA-polymerase can synthesize 10000 nucleotides/second" (I can't find the actual number on the net, but it's crazy high) I solved the problem by not applying at all.
Proper noun examples
More specifically, it's DNA-Polymerase who proofreads.
Frequently asked questions
Short answers drawn from the clearest meanings and examples for this word.
How do you use polymerase in a sentence?
Indeed, 1975 means I would be the first person to think of the idea of Polymerase Chain Reaction!
What does polymerase mean?
(biochemistry) Any of various enzymes that catalyze the formation of polymers of DNA or RNA using an existing strand of RNA or DNA respectively as a template.
What part of speech is polymerase?
polymerase is commonly used as noun.