capsid

Also, the vaccine is made from virus capsid protein expressed in Baker's yeast.

As far as I understand it both ways are based on the drug binding to the capsid, so if the capsid protein changed resistance could evolve.

Polio mutates quickly, but is extremely constrained, almost all mutations are defective, and the capsid structure is highly conserved.

Rhinoviruses (the virus that causes the common cold) are easily aerosolized because they're tiny and are in a protein capsid.

There was some work in rabbits where the authors found an enrichment for mutations in the capsid (the phage's head).

They collectively underscore the importance of investigating capsid-tail interactions and provide a variety of testable predictions.

Before watching the video the notion of interfering with the capsid as a mechanism for stopping the virus made sense.

The phage acquired mutations in its capsid proteins and over several generations blood titers increased by something like two orders of magnitude.

For things that simple, how many ways to build a capsid could there be?

Since HIV is a retrovirus, by the time capsid formation is happening it has already integrated itself with the host cell’s DNA.

Take a look at x-ray crystallography of virus structures - even for non-eveloped capsid structures, there are many regions which can not be resolved.

We next addressed practical constraints arising from the length of DNA that can be physically packaged within a øX174 capsid without impacts to reproductive fitness.

The virus resistant Hawaiian Rainbow Papaya contains a protein from the virus' capsid, effective "vaccinating" the plants, resulting in virus resistance.

"This means that before it can work the virus has already infected the cell and added its RNA to the host cells DNA permanently." is not correct, capsid inhibitors interfere before both reverse transcription and nuclear import.

> It functions by binding to the hydrophobic pocket formed by two neighboring protein subunits in the capsid shell That's entirely cool to me, it operates by exploiting an "incidental construction feature" of the capsid and not targeting any specific feature in and of itself?