homolog

However, such a hypothetical organelle could not be recognized as a mitochondrion homolog by any available means.

That they have homolog levels of substitutability across 35% of the gene is surprising.

A thorough search of current databases failed to find a homolog in any other species with greater than 40% amino acid sequence identity.

Same for homolog, and a few at a time for dev; 2.

It's one thing to work in fly genetics and another to be talking to a parent whose child has a mutation in the human homolog.

Cov2 genome encompassing the furing cleavage site is a 100% complementary match to a codon-optimized proprietary sequence that is the reverse complement of the human mutS homolog (MSH3).

And then, any of the 46 chromosomes (besides the Y chromosome in males) can and do exchange segments with its homolog/sister chromosome of the same type (crossing over or recombination).

On the other hand, homology (or comparative) modelling is a method that generates a structural model of a query sequence based on one or more experimentally solved structure of a close protein homolog.

There’s software that attempts to predict intrinsic disorder based on sequence alone, but in general, in the absence of homolog (evolutionarily related) proteins with known structure you would still need to check experimentally for disorder.

Domains with novel folds usually have a low number of remotely homolog sequences and for that reason the method will fail, not just because they are novel.

That's sometimes a problem for people doing gene knock-out experiments on zebra fish, where you sometimes knock out not only the target but also the homolog because the two are still too similar, despite 425 Myr of evolution.

The first step in AlphaFold is to retrieve as many remotely homolog sequences as possible to generate a multiple sequence alignment (MSA) that will be used to generate the embedding.

He calls it "nitrostyrene (NTS)", which is the one-carbon-shorter homolog.