A cell found in connective tissue that produces fibers, such as collagen.
Used in a Sentence
fibroblast
Definition, parts of speech, synonyms, and sentence examples for fibroblast.
Editorial note
To the entity, the individual is no more important than a random cell in your body (left small toe fibroblast anyone?).
Examples15
Definitions1
Parts of speech1
Quick take
A cell found in connective tissue that produces fibers, such as collagen.
Meaning at a glance
The clearest senses and uses of fibroblast gathered in one view.
Definitions
Core meanings and parts of speech for fibroblast.
noun
A cell found in connective tissue that produces fibers, such as collagen.
Example sentences
To the entity, the individual is no more important than a random cell in your body (left small toe fibroblast anyone?).
In the case of the fibroblast, it's a rather Warhol-esque reconstruction with false colour; the actin in the picture is white, which it couldn't have been in the microscope.
Since mTOR activity is energy-dependent, reduced ATP availability could downregulate mTOR signaling, inhibiting processes like fibroblast proliferation and collagen synthesis.
It enhances release of the basic fibroblast growth factor and inhibits production of transforming growth factor-β1.
The pictures of the dividing cell and the fibroblast are done with a fluorescence microscope, so the colour is a reconstruction of what was there rather than a direct capture.
Your body will direct the peptides to the fibroblast (healing) areas where it is needed.
The dividing cell looks like a projection of a quite thick stack of confocal planes, whereas the fibroblast looks like a single plane.
The effects of Vitamin B3 on fibroblast mitochondrial function in glaucoma patients.
Granted, this too is not completely unreasonable - there are now very robust commercially available protocols for deriving iPSCs from small dermal fibroblast samples.
Fluoroquinolones have been observed to impair collagen synthesis by disrupting the fibroblast function, and this may be due to their impact on the energy-intensive processes governed by mTOR.
* If not, why do you think that transcriptional reprogramming of fibroblast cells in culture (as per the Yang et al.
As an aside, the pictures dividing cell and the fibroblast both look like they were taken with a confocal microscope - there's not enough out-of-plane light for a widefield microscope.
Quote examples
What triggered me was the slide in Sid's presentation: "Assessing Fibroblast Content of Tumor".
The smallest things there are the single cells - the cell dividing, the fibroblast (the "lining the walls of blood vessels" one), the single-celled algae, the Frontonia - and those pictures are all taken with light microscopes.
(Regarding Fibroblast growth factor 21 (FGF21)) key quote: " the metabolic outcomes associated with elevated FGF21 depend on the nutritional context, differing according to whether the animal is in a state of under- or overfeeding." The news article badly misinterprets the results in implying that low protein alone = high FGF21 = longevity.
Frequently asked questions
Short answers drawn from the clearest meanings and examples for this word.
How do you use fibroblast in a sentence?
To the entity, the individual is no more important than a random cell in your body (left small toe fibroblast anyone?).
What does fibroblast mean?
A cell found in connective tissue that produces fibers, such as collagen.
What part of speech is fibroblast?
fibroblast is commonly used as noun.