bioavailability

The bioavailability metric is just plain cheating (or poor math) though since bioavailability is already factored into percent daily value figures.

Whereas with Heroin, a: oral bioavailability is rather low, and b: action happens faster, thus an OD is less likely.

And only generally, some exceptions exist for poor bioavailability due to absorption differences and particular metabolic pathways.

When there is known to be a different bioavailability or digestive response in animals from humans, then the dose is adjusted with that in mind before the experiment begins.

The bioavailability of curcumin (found in turmeric) is much better when taken along with piperine (found in black pepper).

Was it just that the penicillin salts they were using at the time had low bioavailability?

Curcumin is poorly absorbed but there are several ways to increase the bioavailability[1].

Here's another complex multi-syllable word that's worth of study by HN moderators: bioavailability.

What may be interpreted as tolerance is actually a circumstantial lack of bioavailability.

For example, the combination of turmeric and black pepper in curry is now scientifically proven to increase curcumin's bioavailability by orders of magnitude.

Magnesium is worth checking out as well, even if you're eating a proper diet (nutrient bioavailability can be affected by a lot of things).

So I looked into this and found that D2 has poor bioavailability and depletes magnesium.

The old saying that "the dose makes the poison" probably applies here, and bioavailability of the arsenic forms probably plays a role.

I sincerely doubt any diet rich in (reasonably fatty, reasonably "unprocessed") meat would show a Vitamin A deficiency, unless too much of such plant matter as hampers bioavailability and absorption is consumed concurrently.