Senescent used in a sentence

Senescent in a sentence as an adjective

Then figure out some way to flush out senescent cells

The team suspected that senescent cells' resistance to death by stress and damage could provide a clue.

> As for the longer senescent, ... "senescent" is an adjective, and means "growing old.

Some species live longer than us; and some are even negligibly senescent[0]!4.

I'd rather live 80 years in a body that worked as if it was still in its thirties, than 500 years in a senescent body.

I wonder if low dose radation or low dose toxins that foster hormesis are actually killing off these senescent cells.

The scientists were faced with the question, though, of how to identify and target senescent cells without damaging other cells.

All of these are also good for you, but the senescent cell model was the first one to suggest a mechanism of action for hormesis to me.

A method of targeting senescent cells for destruction was recently published, and we can expect to see more diverse attempts at this in the next few years.

When conditions change, a senescent species can drive immortal competitors to extinction.

So your greying, senescent population can go ahead and stay at home without affecting anything regarding mankind's future.

For example, clearance of senescent cells, an approach which has just now reached the point of credible demonstrations in normal mice, but needs much more support to make it into the mainstream.

The most advanced of the necessary lines of research is ablation of senescent cells, which has been shown to work in accelerated aging mice and is current in studies in normal mice.

To my eyes, the important outcome here is the development of a reliable way to flush out senescent cells in mice - which can now be applied to otherwise normal mice to see what happens there.

Indeed, using transcript analysis, the researchers found that, like cancer cells, senescent cells have increased expression of "pro-survival networks" that help them resist apoptosis or programmed cell death.

Well, they don't allow interventions that require daily injections, etc, but the implication seems to be that something that requires a once-a-month injection, such as senescent cell clearance, would likely be allowed.

Dasatinib eliminated senescent human fat cell progenitors, while quercetin was more effective against senescent human endothelial cells and mouse bone marrow stem cells.

However, whether senescent cells are causally implicated in age-related dysfunction and whether their removal is beneficial has remained unknown.

This sort of thing is underway in the cancer research community, and the technologies produced will have very broad application: safe and painless removal of immune cells, fat cells, senescent cells - anything we don't want and can be distinguished.

The world's oldest person will experience life like this: about 110 years of natural aging, followed by some experimental new treatments that keep that person in a senescent state for about 10-15 years, followed by a reversion, probably returning to the health of an average 20-year-old by age 140.

The mice used in this study are a breed engineered to suffer accelerated aging, which means it doesn't have too much to say about what will happen in normal mice: this study adds weight to arguments for the importance of senescent cells in aging by virtue of the degree of change that was produced.

We have the early demonstration that targeted removal of senescent cells extends life in accelerated aging mice [1], for example, and ample reason to believe it is beneficial for ordinary individuals, but it took philanthropic funding to move that research forward at all.

At some point it will become evident to the public and the world at large that aging to death whilst surrounding by wealth is insanity in an age in which those resources could be used for the development of age-reversing medicine: ways to repair mitochondrial DNA, break down accumulated metabolic byproducts that clog up cells, clear out senescent cells, restore declining stem cell activity, and so forth.