humoral

The intramuscular's humoral) immunity against severe disease in the body serum and organs holds up pretty well.

In intramuscular vaccination (with whatever delivery method you want) you generate humoral IgG antibodies (to go with the IgM).

For me it's not over till there's an FDA approved intranasal sars-cov-2 vaccine (mucosal) to complement the intramuscular (humoral) one.

Plenty of studies show failure to form humoral responses to natural infection, particularly with mild infection.

Intramuscular vaccinations do not significantly prevent infection of the upper respiratory immune compartment (mucosal IgA antibodies, not humoral covered by IgG).

While chronic gut inflammation will affect vascular health in the brain through the humoral response.

Brief naturalistic stressors (such as exams) tended to suppress cellular immunity while preserving humoral immunity.

The more likely guess is that once you have humoral/serum immunity to protect the body proper you just get the upper respiratory infection (since mucosal tissues are not protected by humoral immunity significantly).

He's talking about the IgA antibodies generated in mucosal tissues with the IgM that's in both mucosal and humoral body immune compartments.

My humoral tissues / organs should be fine thanks to the intramuscular vaccinations.

But the lower lungs already get seepage of body serum/humoral igM and igG.

It's much more nuanced really, but humoral immunity in particular wanes with time.

If the disease is "too much humoral blood" the treatment is then the leech to lower that blood.

And all Viruses are hard to get to when they are inside a cell, which is why the immune system mainly uses cell targeting mechanisms to get rid of viral infections, rather than the "humoral" defense of free floating antibodies (simplifying by a lot here).

Humoral vaccines do provide some limited protection when it comes to transmission.