Senescence used in a sentence

Senescence in a sentence as a noun

And for a child born today, I hope that senescence will become a solvable problem within its lifetime.

If we could effectively halt senescence, we'd be able to expend fewer resources on care for the elderly.

People who train with weights live longer, with fewer health problems, with shorter senescence, than people who don't. These health effects are distinct from the health effects of non-resistance training such as running, cycling or swimming.

Given how little we know about stopping aging, and that blocking senescence also requires having a cure for cancer which society has thus far failed to find after spending something like $10B a year on it, I'm extremely skeptical of your claim about cost and time frame. Do you have a source for that?

Longer lived people have more memories and skills, so of course our capacity would increase -- if not counteracted by neurological senescence. The trick is to regenerate the person to a youthful state, where they can be productive and creative yet retain their knowledge and skills.

The authors misunderstood the evolutionary theory of senescence. Furthermore, they failed to account for other behavioral attributes of the folks being studied.

Only if you also eliminate senescence -- cells generally lose the ability to divide over time, and a whole bunch of creeping malfunctions result in us breaking down towards a limiting age of 114.

It is the immune system's job to **** off these lost cause cells - and the precancerous cells, and *** a bunch of other problems in the bud while it's at it - but the immune system becomes increasingly weak with age, and hence the growth in the number of unculled senescence cells. These cells sit in tissue as increasingly bad actors, well past their sell-by date, taking actions that harm surrounding cells and structures.

By "death", I assume you mean senescence: the natural biomolecular attrition that inexorably leads to organismal death absent of outside causes. It is true that turtles can live for almost 200 years and some plants can live for thousands of years. If we are essentially, biochemically the same, we could in theory overcome our biochemical "bugs" to achieve negligible senescence.

Some kind of medical intervention that targeted the actual senescence mechanism instead of just the other problems it causes would be an actual game-changer, and I don't see how we could get living past 100 to be very probable without coming up with one.

There's a great diversity in lifespan among organisms, which is a good clue, but the number of organisms that actually show no senescence is quite small, and they are all very distant from humans evolutionarily. Those few have been studied heavily in aging, but trying to extrapolate differences in these organisms to humans is very challenging because they have totally different anatomies, genomes, and sets of proteins.

So while I'm going to cling to life as bitterly as I can as long as I can -- my own goal is to see the tricentennial, the dawn of the 22nd century, and maybe the transit of Venus, which I missed this year -- my personal immortality likely depends on not just discovering a safe way to halt aging and prolong life, but a way to reverse senescence and restore youth. I think it's possible, but forecasting it as happening before I die is a bit cliche in this domain.

Quote Examples using Senescence

In terms of actually slowing down senescence, or the 9%/year increase in death rate, we haven't. We don't have the tools yet. At some point, people will. I'm 50-50 about whether I'll "make the cut" but choose to live as if I won't, for obvious reasons. I am not even guaranteed a day; no one is. I think that the tools to slow senescence will be developed a few years before it becomes possible to halt and reverse aging outright.

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