Placebo used in a sentence

Placebo in a sentence as a noun

And while that can have a placebo effect, it's not more value.

I did, however, try to assess the placebo effect in a couple of sneaky ways.

If placebos are sugar pills, they don't need regulation.

Second, there is a known effect -- the placebo effect -- that can affect results.

As explained elsewhere, you give the vaccine and a placebo to an at-risk.

The only way to do that is to release the ingredients used in the creation of placebos.

They are going to be using active placebos for phase III, which are much more effective for blinding.

And it might just be a placebo, but it makes me feel like the site functions are more testable and compartmentalized.

"The patients in the placebo group improved, too; so a large part of the benefit could be attributed to the psychotherapy.

To me, that really sounds like you may psyche yourself out. ie. that you worry about MSG so much that it starts to cause you stress about it, and it's a self-fulfilling prophecy/placebo effect/whatever.

"Actually what it says is that placebo ingredients should be documented in studies, and regulated by the FDA. Why is that such heresy?

Alternatively, working against it was the concern they were getting the placebo and likelihood of getting worse.

Variations in the effect of placebo were partly explained by variations in how trials were conducted and how patients were informed.

So often a drug will be better than a placebo in only 2 out of 10 trials, but it will still get approved and only those two trials will get published in medical journals.

I do know friends and family who have benefited from psychiatric medications, although that could entirely be due to placebo effect.

First and foremost is that if the drug really works, it would be unethical to leave people on a placebo for long periods, because it is clear they have an inferior outcome.

If you think trained scientists couldn't possibly stumble on that kind of pitfall, you should read about N-rays[1].This is just as likely to be true for the "nocebo" effect as for the placebo effect.

Alternatively, placebo effect now only has working against it the "off chance" that if the patient gets the placebo he also does not experience the placebo effect.

The possible exception to this are the subjective symptoms of pain and nausea, where the placebo effects are highly variable and may be due to subjective reporting.

The reason is placebos are receiving meta enhancement!At first the placebo effect only had working for it the patients hope that they might be receiving the treatment pill and might get better.

But if you hear of a placebo doing something and you think "how could a belief in a placebo possibly have that kind of effect", it's very likely that you are at least partly seeing mere measurement error.

So now, the placebo has working for it the patients hope of getting the treatment and getting better plus the hope that in the case they get the placebo they experience the placebo effect and get better anyways.

For objective physiological outcomes, there is no significant placebo effect.

It appears that a lot of participants on Hacker News are interested in the role of placebos in treatment trials. I have some recommendations for background articles on the use of placebos in clinical trials and the pitfalls sometimes encountered in interpreting results from such trials.

It is plausible that some specific placebo effects like reduction/increase of pain response, anxiety, and mood could actually be real psychological effects involving suggestion.

Another comment already posted here on HN has pointed out that the FDA does oversee what ingredients are put into placebos, whether or not those detailed ingredients are published in a peer-reviewed research study.

One really important point about the placebo effect that a lot of people miss is that a lot of it is not a real physiological change caused by the placebo, but is a result of bias in both the subject and the experimenter.

However, in certain settings placebo interventions can influence patient-reported outcomes, especially pain and nausea, though it is difficult to distinguish patient-reported effects of placebo from biased reporting.

How can anyone, including you, know how effective the choice of placebo ingredients are if they aren't disclosed?It doesn't seem an undue burden to ask that the placebo ingredients be documented so that their effect on the study, which is critical by any measure, can be understood.

"Fabrizio Benedetti, a co-author of one of the most cited papers who is also a medical doctor, sums up his view this way: "I am a doctor, it is true, but I am mainly a neurophysiologist, so I use the placebo response as a model to understand how our brain works.

They tend to “outpace” the scientific literature, using some substances that haven’t yet been shown to work, or haven’t been shown to benefit healthy individuals.\n...\n" I would have liked to have some placebo nootropics to use as a comparison, but since I wasn’t running a trial, I didn’t have that option.

And then those journal articles will have very little in common with the actual data from the FDA trials because the pharma companies completely spin it, which is why the vast majority of the most popularly prescribed ***** are not only no more effective than placebos, but in fact significantly worse when you look at the total quality/length of life.