globin

Granted some things are more likely (oxygen-binding hemoglobin has independently evolved several times from its related non-binding globin family).

There’s 574 amino acids making four separate interlocking chains in a single globin, plus the heme, all just to bind 4 oxygen molecules.

Detects globin at 50 ng/mL and is board approved by gastroenterologists.

Unfortunately globin switch is epigenetic / in histone coding...

Sickle cell trait (being heterozygous for the gene that replaces beta-globin with hemoglobin S) protects against anemia, and does not, in and of itself, produce sickle cell disease.

We're a long way off since globin expression is wrong (fetal vs adult; thus O2 binding kinetics are wrong; T/R states...), and there are a wide variety of other issues.

> Fresh or marinated meat: Iron in the myoglobin changes from ferrous to ferric and globin is denatured-the red color is lost.

The globin protein is going to be digested in the stomach and broken down into its constituent aminoacids (which are exactly the same as the one found in other proteins).

Furthermore, the endogenous delta-globin gene (HBD), which is homologous to HBB, competed with exogenous donor oligos to act as the repair template, leading to untoward mutations.

"We describe our first patient treated with lentiviral vector–mediated addition of an antisickling β-globin gene into autologous hematopoietic stem cells."

I think as a non-medical term "blood" is potentially broad enough to cover both hemo- and myo-globin.

According to Wiki, "Sickle cell disease occurs when a person inherits two abnormal copies of the β-globin gene (HBB) that makes haemoglobin, one from each parent".

According to Wiki: "Sickle cell disease occurs when a person inherits two abnormal copies of the β-globin gene (HBB) that makes haemoglobin, one from each parent".