xenobiotic

Humans and rats consume lots of xenobiotics due to our versatile diets - neuroscience, anything below the prefrontal cortex is pretty well conserved between rats and primates - cancer - kinda garbage. Mice and rats get cancer at the drop of a hat.

Intestinal bacteria also have a role in the synthesis of vitamins B and K and the metabolism of bile acids, other sterols and xenobiotics. The colonic microflora are also responsive to diet.

> "Vyvanse is just a more concentrated version of the d-enantiomer" Not at all; it's a prodrug that is converted into the d-enantiomer by your liver, at whatever your xenobiotic-metabolic speed is. The major result of this has nothing to do with how safe a regular pill-dose of Vyvanse is vs.

The research you mentioned specifies in the abstract a probable cause for failing to replicate the same conditions for the experiment:\n It is possible that during a colony conversion the supplier inadvertently introduced strain differences making the present rats more resistant to xenobiotic consumption. In my opinion this tells a lot.

The liver is dedicated to metabolizing these substances, in a process literally called "xenobiotic metabolism". Sure, the odds of a particular compound found in some alien lifeform having a toxic interaction with our bodies is small, but I consider the odds of one of the hundreds of thousands of different types of compounds in that lifeform having a toxic interaction is on the higher side.

Gut microbiome is a complex ecosystem where 1014 microorganisms play several roles in host nutrition, bone mineralization, immune system regulation, xenobiotics metabolism, proliferation of intestinal cells, and protection against pathogens. A disruption in composition of the normal microbiota is known as ‘gut dysbiosis’ which may adversely affect body metabolism.