xenografts

This has been proven out already as a strategy by another company using xenografts, Champions Oncology.

Even with using xenografts instead of cell lines there's plenty of stuff that can go wrong.

Most cancer studies in mice are xenografts of human cancer cells so any relevance of mice telomeres is completely lost anyway.

As mattkrause notes below, that number is for mice with human tumor xenografts.

Not just mice but transgenic mice, or nude mice with xenografts, etc.

The monkeys survived for up to two years with the xenografts.

Cloned mice receive tumor grown on human derived tissue so-called xenografts.

If I had to put money on it, I’d bet that the xenografts win.

> They have also developed a way of ensuring the kangaroo xenografts are not rejected after transplant.

That makes studies like the one cited here -- which involve the cancer-fighting activity of a mouse's own immune cells -- difficult to do with human xenografts.

We'll also be using in vivo xenografts to try to model mutations/regrowths, by continuously observing treated mice to see if we get a regrowth.

Amazing times indeed, we are seeing xenografts and artificial organs in use.

This isn't quite as bad as the garden variety "in mice" studies: > The combination therapy also led to significant regression in genetically engineered mouse tumours and in human cancer tissues grown in lab mice, known as patient-derived tumour xenografts (PDX).

Xenografts need skilled labor and very clean conditions for the immunocompromised mice.