despair

It seems most of his despair revolves around the sense of having "lost" and being overtaken by events.

People who are almost constantly doused in worry, panic and despair, even when spending quality time with those they love.

But that endless well of despair still sits there, but it's like I'm walking around the edge of it, like walking around the edge of a swimming pool, trying to make sure I don't fall or jump in.

That’s somewhat understandable, because there are many moments that are filled with despair and agony, when you have to fire people and cancel things and deal with very difficult situations.

This is established medical fact and is taught in all medical schools now. However I worry that it might make people consider heroin as something that will be okay to have a crack at... There are very real psychosocial dangers of heroin should you end up being dependent and addicted - and the depths of despair that users end up in should not be ignored.

The person is, to me, a person and a patient, but I cannot be expected to have the same dark despair as I would, had I lost a long and close friend, and it makes me no less emotional or human to not have that response.

She is a portrait of misery, holding back tears during the exam, profusely apologetic for coming in, this is her first infection in 2 years and she's just in absolute despair because she doesn't want more surgery, and begs for the antibiotic only because the antibiotic-steroid combo, in her experience, hurts more and promises she will got to the ER if she gets a headache.